Cialis (Tadalafil) 5 mg (EU)

Common use

Cialis is an effective, reversible, selective inhibitor of phosphodiesterase type 5 (PDE 5) specific to cyclic guanosine monophosphate (cGMP). When sexual stimulation causes local release of nitric oxide, inhibition of PDE 5 by Cialis leads to increase of cGMP levels in the cavernous body of penis. It results in the relaxation of arterial smooth muscles and blood flow to the tissues of the penis that causes erections. Cialis has no effect when sexual stimulation is absent. Cialis improves erection and let's achieve a successful sexual intercourse. The drug acts for 36 hours. If sexual arousal is present the effect appears even after 16 minutes after the medication was taken.

Dosage and direction

The recommended dose of Cialis is 20 mg it should be taken at least 16 minutes before the sexual activity. The effect persists for 36 hours. Take Cialis once daily and do not exceed the recommended dose.

Precautions

It is preferable not to use Cialis with grapefruit juice, alcoholic beverages, tobacco. If you smoke tobacco and take Cialis concomitantly this may lead to a condition called NAION (sudden optic nerve-related vision loss). Inform your doctor before to take. Cialis if you have abnormal penis, including curved penis and birth defects of the penis, had coronary artery disease, arrhythmia, angina, heart attack or heart failure, hypo- or hypertension, bleeding, stomach ulcers, diabetes, hyperlipidemia (excess of lipids in the blood), sickle-cell anaemia, liver or kidney failure in history.

Side effects of Cialis Generic might include:

• nausea, upset stomach, diarrhoea;
• facial redness, headache and diverse flu-like symptoms;
• blurred vision or changed colour perception;
• sometimes low blood pressure;
• abnormal ejaculation or priapism (a prolonged and painful erection that must be reported to a doctor if does not disappear for more than 4 hours, otherwise it may cause damage to the penis).

To decrease the risk of developing side effects, it is required that your doctor authorized treatment with Cialis Generic if you:

• have congenital defects or curved penis;
• suffer from diabetes, liver/heart/vessels conditions, stomach ulcer, hypo- or hypertension, hyperlipidemia, or sickle-cell anaemia;
• are a smoker, like smoking tobacco during treatment with Cialis Generic may cause sudden optic nerve-related vision loss;
• are exposed to or taking any organic nitrates as it may cause severe hypotension that might be dangerous;
• are taking medications or substances containing terazosin, saquinavir, itraconazole, pentaerythritol tetranitrate, erythritol tetranitrate, nitroglycerin, erythromycin, ketoconazole, atazanavir, bunazosin, doxazosin, itraconazole, moxisylyte, indinavir, phenoxybenzamine, trimazosin, urapidil, telithromycin, phentolamine, nefazodone or ritonavir.

Drug interactions

Co-administration with medications containing organic nitrates may cause severe hypotension which is dangerous in some cases. Avoid taking Calis with medications such as Erythrityl Tetranitrate, Isosorbide Dinitrate, Isosorbide Mononitrate, Nitroglycerin, Pentaerythritol Tetranitrate. Levels and toxicity of Cialis are increased by erythromycin, ketoconazole (Nizoral), itraconazole (Sporanox), indinavir (Crixivan) and ritonavir (Norvir). Inform your doctor if you are taking Atazanavir, Bunazosin, Clarithromycin, Doxazosin, Erythromycin, Indinavir, Itraconazole, Ketoconazole, Moxisylyte, Nefazodone, Nelfinavir, Phenoxybenzamine, Phentolamine, Prazosin, Saquinavir, Telithromycin, Terazosin, Trimazosin, Urapidil as your Cialis dose may require correction.

Missed dose

Missed dose is not supposed if Cialis is taken for treatment of erectile dysfunction as it s used when needed.

Overdose

Overdose of Cialis causes symptoms described as side effects. Seek for immediate medical help if you by your opinion you took too much of this medication.

Storage

Store at room temperature away from moisture, sunlight, kids and pets in a tight container.